Effect of platelet rich plasma on treatment of knee osteoarthritis

The comparison of platelet rich plasma injection versus exercise therapy with TENS modality in improvement of sign and symptoms among patients with osteoarthritis of knee, a randomized clinical trial in Rasoul Akram hospital

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2012110611382N1

Enrollment

Registered

2012-12-04

Start date

2012-12-01

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

knee osteoarthritis. Primary gonarthrosis

Interventions

Intervention 1: intraknee injection of platelet rich plasma. Intervention 2: Trans Epidermal Nerve Stimulation(TENS) Exercise Therapy.

Treatment - Other

Rehabilitation

intraknee injection of platelet rich plasma

Trans Epidermal Nerve Stimulation(TENS) Exercise Therapy

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Inclusion criteria: Male and female with knee pain in stage 1-3 kellgren Lawrence?no history of intraknee injection of steroids within last three months; no history of spinal stenosis; no history of blood discrasy and consumption of anticuagulative drugs Exclusion criteria : Inability for physical activity; patient's request to leave study; intraknee injection of steroids during study; suffering debilitating diseases during study that interfere with patient's physical activity; applying pacemaker due to physical condition during the study

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Knee pain. Timepoint: before the intervention then 4 and 8 weeks after the begining of the intervention. Method of measurement: vas form.;Morning stifness. Timepoint: before the intervention then 4 and 8 weeks after the begining of the intervention. Method of measurement: standardized koos questionnaire.;ROM improvement. Timepoint: before the intervention then 4 and 8 weeks after the begining of the intervention. Method of measurement: standardized koos questionnaire.;Intolerable pain inception time in treadmill walking test. Timepoint: before the intervention then 4 and 8 weeks after the begining of the intervention. Method of measurement: walking on tredmill.	—

Measure

Time frame

Knee pain. Timepoint: before the intervention then 4 and 8 weeks after the begining of the intervention. Method of measurement: vas form.;Morning stifness. Timepoint: before the intervention then 4 and 8 weeks after the begining of the intervention. Method of measurement: standardized koos questionnaire.;ROM improvement. Timepoint: before the intervention then 4 and 8 weeks after the begining of the intervention. Method of measurement: standardized koos questionnaire.;Intolerable pain inception time in treadmill walking test. Timepoint: before the intervention then 4 and 8 weeks after the begining of the intervention. Method of measurement: walking on tredmill.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr.Omid Marjomaki

Rasoul Akram Hospital

marjomaki@gmail.com+98 21 6435 2446

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026