Evaluating the effectiveness of zinc Sulfate in Improvement in Depressive Symptoms in Patients Treated with Selective Serotonin Reuptake inhibitors in Ahvaz Golestan Hospital

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2012110411363N1

Enrollment

Registered

2017-10-04

Start date

2016-04-04

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Major Depresion. Severe depressive episode without psychotic symptoms

Interventions

Intervention 1: Taking a Zinc sulfate capsule, 25 mg once a day for 8 weeks (intervention). Intervention 2: Taking a Malt Dexterous placebo once a day for 8 weeks.

Treatment - Drugs

Placebo

Taking a Zinc sulfate capsule, 25 mg once a day for 8 weeks (intervention)

Taking a Malt Dexterous placebo once a day for 8 weeks

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Age 18- 80 years; diagnosis of depression based on DSMVITR; Exclusion criteria: neurological complications; chronic physiological diseases; current addiction to opium or alcohol; history of addiction to opium or alcohol in the past 6 months; history of allergy to antidepressants or zine sulfate; use of monoxide inhibitor in the past 8 weeks; history of seizure; history of suicide; liver, renal or cardiac disorder; pregnancy or breast feeding.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Depresion Status. Timepoint: 2,4,6,and 8th weeks. Method of measurement: Beck Depression Rating Scale.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMasoume Nazarinasab

Ahvaz Jundishapur University of Medical Sciences

Nazarinasab-m@ajums.ac.ir+98 61 3587 4366

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026