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Efficacy of oral tizanidine for postoperative pain in perianal surgery.

Efficacy of oral tizanidine for postoperative pain in perianal surgery.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201210315381N3
Enrollment
60
Registered
2012-12-23
Start date
2012-07-31
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

preanal surgery. disease of anus and rectum,unspecified

Interventions

Intervention 1: intervention:tizanidine,4 mg,one hour before surgery. Intervention 2: control:plasebo,one hour before surgery.
Treatment - Drugs
intervention:tizanidine,4 mg,one hour before surgery.
control:plasebo,one hour before surgery.

Sponsors

Vice-chancellor Of Research Babol University Of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
20 Years to 55 Years

Inclusion criteria

Inclusion criteria: The inclusion criteria :patients of candidate of perianal surgery; males; ASA I-II; elective surgery; 20-55 years exclusion criteria:,psychology disorder; addiction; history of allergy; history of hypertension; drug history of clonidine and tizanidine; surgery duration longer than 2 hours.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Pain severity. Timepoint: From the first hour after surgery for 24 hours, every 8 hour. Method of measurement: visul analoge scale.;Meperidine consumption. Timepoint: 24 hours. Method of measurement: meperidine consumption(mg).

Secondary

MeasureTime frame
Patient's hemodynamics. Timepoint: 24 hours after surgery. Method of measurement: Blood pressure and heart rate were evaluated by digital monitoring devices.;Nausea, vomiting. Timepoint: 24 hours. Method of measurement: Through a questionnaire and observation.

Countries

Iran (Islamic Republic of)

Contacts

Public Contactdr nadia banihashem

Babol University Of Medical Sciences

nbanihashem@yahoo.com+98 11 1223 8296

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026