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Efficacy and complications of morphine suppository

Comparison of efficacy and side effects of morphine and diclofenac suppositories in post operative pain after appendectomy and inguinal hernia surgery in Fatemi hospital

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2012103111338N1
Enrollment
75
Registered
2014-05-24
Start date
2013-05-22
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

acute postoperative pain.

Interventions

Intervention 1: first group received morphine suppositories (10mg) in 2, 6, 12, 24 hours post operation if VAS>4.0. Intervention 2: second group received diclofenac suppositories (100mg) in 2, 6, 12
Treatment - Drugs
first group received morphine suppositories (10mg) in 2, 6, 12, 24 hours post operation if VAS>4.0
second group received diclofenac suppositories (100mg) in 2, 6, 12, 24 hours post operation if VAS>4.0
In third group, to control of pain (VAS>4) received intramuscular pethidine (50mg) Prn

Sponsors

Ardabil University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: patients who are candidates for appendectomy and inguinal hernia surgery ?Patients aged 70-18 years?Patients without underlying disease and drug consumption Exclusion criteria: Pregnant patients? patients with neurological disease or psychiatric disorders, patients with a history of seizures? patients with acute or chronic renal disease? patients with a history of peptic ulcer ? patients with taking psychotropic drugs? abused alcohol or opioid drugs?,Hemorrhoid disease or disorder in anus

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Pain intensity(VAS). Timepoint: in 2, 6, 12, 24 hours post operation. Method of measurement: based on graded ruler 0-10.

Secondary

MeasureTime frame
1-sedation 2-nausea and vomiting. Timepoint: in 2, 6, 12, 24 hours post operation. Method of measurement: based on Ramsay Sedation Scale(0-5).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Godrat Akhavan Akbari

Ardabil University of Medical Sciences

g.akbari@arums.ac.ir+98 45 1223 2521

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026