Evaluation the effect of nasal spray based on herbal extracts on the treatment of chronic rhinosinusitis.

Evaluation the effect of nasal spray based on herbal extracts (a traditional Persian medicine formulation) on the treatment of chronic rhinosinusitis, A multicentral randomized double blind placebo-controlled clinical trial

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20121031011341N13

Enrollment

Registered

2024-06-08

Start date

2024-06-21

Completion date

Unknown

Last updated

2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic rhinosinusitis. Chronic rhinitis

Interventions

Intervention 1: Intervention group: patients were treated for 3 weeks by nasal spray based on traditional persian medicine 2puff on each nostril for each 8 hours. Intervention 2: Control group: patien

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Patients with chronic rhinosinusitis without nasal polyposis Lund- Mckay score more than 3 in PNS CT Scan Full consciousness and sign a written consent for participation in the study

Exclusion criteria

Exclusion criteria: Patients with history of previous sinus surgery Pregnant patients or breastfeeding mothers Patients with Samter triad (asthma, allergy to aspirin, nasal polyposis) People who refuse to be involved in this research study

Design outcomes

Primary

Measure	Time frame
Sign & symptom of disease. Timepoint: 3 weeks after intervention. Method of measurement: SNOT 22 questionnaire.;Quality of life of patients. Timepoint: 3 weeks after intervention. Method of measurement: RhinoQOL questionnaire.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Hashem Hashempur

Shiraz University of Medical Sciences

hashempur@gmail.com+98 71 3230 5410

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026