Post operative analgesia after total abdominal hysterectomy. Acquired absence of uterus
Conditions
Interventions
Intervention 1: Apotel in case group. Intervention 2: Ketamine in control group.
Treatment - Drugs
Apotel in case group
Ketamine in control group
Sponsors
Research Deputy, Tehran University of Medical Sciences (TUMS)
Eligibility
Sex/Gender
Female
Age
25 Years to 65 Years
Inclusion criteria
Inclusion criteria: inclusion criteria: 1-Volunteers ages between 25-65; 2- American Society of Anesthesiologist class (ASA) I, II Physical Status; 3- Scheduled for total abdominal hysterectomy surgery; 4- Written informed consent , based on Tehran University Mdical Sciences , Ethical Committee Appproved Study design. Exclusion Criteria: 1-Out of 25-65 ages limitations; 2- Addiction to opiates; 3- Known allergy to acetaminophen or ketamine; 4- History of alcoholism and drug abuse; 5- History of hepatic disease; 6- Dispensing of patient any time after informed consent or lack of patient consent; 7- History of sizure
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain. Timepoint: At recovery room, 4, 6, 12 and 24 o'clock after surgery. Method of measurement: Visual Analoge Scsale. | — |
Secondary
| Measure | Time frame |
|---|---|
| The patients will evaluate for Sedation, Nausea and Vomiting, additional requirement for analgesia and probable complication during study includes of: pruritus and other complication in both groups. Timepoint: At recovery room, 4, 6, 12 and 24 o'clock after surgery. Method of measurement: Score of seadtion and nausea and vomiting type and dosage of additional analgesic. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactHamid Reza Feiz
Tehran University of Medical ciences
Outcome results
None listed