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comparison of Misoprostol with Oxytocin on labor augmentation in pregnant women

comparison the effect of oral Misoprostol versus Oxytocin on labor augmentation in pregnant women

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
IRCT
Registry ID
IRCT2012102910068N2
Enrollment
250
Registered
2012-11-28
Start date
2009-01-01
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Long labour. Prolonged second stage (of labour)

Interventions

Intervention 1: In the misoprostol group, a tablet of 200 µg was dissolved in 200cc of water and 25cc was administered every two hours for up to 24 hours. The maximum dose was 300 µg. Fetal heart moni
Treatment - Drugs
In the misoprostol group, a tablet of 200 µg was dissolved in 200cc of water and 25cc was administered every two hours for up to 24 hours. The maximum dose was 300 µg. Fetal heart monitoring and uter

Sponsors

Shahid Beheshti University of Medical Science
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
16 Years to 45 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: pregnancy between 36 and 42 weeks of gestation; a live singleton fetus in cephalic presentation; no history of uterine surgery; spontaneous onset of active labor with regular contractions; an effaced cervix dilated between 3 cm and 9 cm; a reassuring fetal heart rate (FHR) pattern. Exclusion criteria: nonreassuring FHR pattern; parity greater than five; any contraindication to labor or vaginal delivery or both; epidural analgesia; significant maternal cardiac; renal or hepatic disease; hypersensitivity to misoprostol or prostaglandin analogues.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
The time from augmentation to vaginal delivery. Timepoint: 12 and 24 hours during labor. Method of measurement: data recording.;Mode of delivery. Timepoint: 12 and 24 hours during labor. Method of measurement: data recording.

Secondary

MeasureTime frame
Fetal and neonatal status. Timepoint: peri labor phase. Method of measurement: data record.;Maternal complications. Timepoint: peri labor phase. Method of measurement: data record.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAida Moeini

Department of Obstetrics and Gynecology, Shahid Beheshti University of Medical Science

a.moeini64@gmail.com+98 21 2271 8000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026