Postoperative Pain. Acute pain
Conditions
Interventions
Intervention 1: infusion of magnesium sulphate 40 miligram per kilogram before induction and then 15 miligram per kilogram per hour infusion during the operation until the 20 min after the end of sur
Treatment - Drugs
infusion of magnesium sulphate 40 miligram per kilogram before induction and then 15 miligram per kilogram per hour infusion during the operation until the 20 min after the end of surgery
Infusion of isotonic saline 100 mililitre before induction and then 100 mililitre per hour infusion during the operation until the 20 min after the end of surgery
Sponsors
Vice chancellor for research of Ahvaz Jondishapour University of Medical Sciences
Eligibility
Sex/Gender
All
Age
16 Years to 60 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: patients with ASA 1 or 2 ; the patients without history of drug abuse ; without sensitivity to magnesium , opioids and analgesics ; any hepatic, renal, cardiovascular, neuromascular or neurological disorder ; not to use calcium channel blockers Exclusion criteria: patients with preoperative hemodynamic instability ; preoperative respiratory distress; preoperative nausea and vomiting or any important adverse effects ; patients with magnesium infusion time less than one hour and more than 3 hours.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain score. Timepoint: 30 min , 2 hours, 6 hours, 12 hours, 24 hours after surgery. Method of measurement: Visual analogue scale. | — |
Secondary
| Measure | Time frame |
|---|---|
| Meperidine consumption. Timepoint: in 24 hours after surgery. Method of measurement: milligramms.;Incidence of adverse effects. Timepoint: In 24 hours after surgery. Method of measurement: Asking from patients. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactZeinab Alizadeh
Ahvaz Jondishapour University of Medical Sciences
Outcome results
None listed