Female Infertility. Complications of attempted introduction of embryo in embryo transfer
Conditions
Interventions
Intervention 1: For group I start 2mg estradiol valerat (tablet) from first to 4th day of the menstrual cycle, and continue by 4mg from 5th to 8th day, and 6mg from 9th to 20th day of th
Treatment - Drugs
In the group II in addition to the above treatment protocol, from first day of cycle until the day of starting progesterone will be given 50mg sildenafil citrate tablets daily and
For group I start 2mg estradiol valerat (tablet) from first to 4th day of the menstrual cycle, and continue by 4mg from 5th to 8th day, and 6mg from 9th to 20th day of the menstrual cycl
Sponsors
Yazd Shahid Sadoughi University of Medical Sciences and Health Services, Vice Chancellor for resear
Eligibility
Sex/Gender
Female
Age
15 Years to 40 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: All infertile women have high quality frozen embryos. Exclusion criteria: 1. Age> 40 2. History of endocrine disease such as: diabetes; Hyperthyroidism and Hyperprolactinemia 3. History of hysteroscopic surgery due to intrauterine adhesions 4. History of cardiovascular, renal or liver disease 5. Hypotension( blood pressure<90/50) 6. History of stroke or myocardial infarction 7. Poor quality embryos 8. Alcohol or Substance abuse
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Endometrial thickness. Timepoint: ?Within a day from 13th day of the menstrual cycle. Method of measurement: Vaginal sonoghraphy.;Chemical pregnancy. Timepoint: Two weeks after embryo transfer. Method of measurement: BHCG test. | — |
Secondary
| Measure | Time frame |
|---|---|
| Duration of infertility. Timepoint: Before intervention. Method of measurement: Patient's medical record.;Implantation rate. Timepoint: Four weeks after the embryo transfer. Method of measurement: Number of gestational sac are determined by vaginal ultrasound.;FSH, LH, FSH/LH level. Timepoint: ratio in progesterone day administration. Method of measurement: Blood sample. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Razieh Dehghani Firouzabadi
Yazd Research and Clinical Center for Infertility, Shahid Sadoughi University of Medical Sciences
Outcome results
None listed