comparison of crystalloid and colloid solutions effect on clot formation time and clot firmness after 10 minutes during the upper or lower limbs surgeries

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT201210223773N6

Enrollment

Registered

2013-03-10

Start date

2012-11-21

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: clot firmness after 10 minutes. Condition 2: clot formation time. Haemorrhagic condition, unspecified Consumption coagulopathy

Interventions

Intervention 1: The first group will receive only crystalloid solutions. Solutions will be prescribed to the 55 ml / kg. Once before and one hour after administration of the solution, blood samples w

Treatment - Drugs

The first group will receive only crystalloid solutions. Solutions will be prescribed to the 55 ml / kg. Once before and one hour after administration of the solution, blood samples will be taken fr

Solutions will be prescribed to the 55 ml / kg. Once before and one hour after administration of the solution, blood samples will be taken from three groups of patients. Using Fibtem inhibitor solutio

third group will receive hydroxyethyl Starch6%. Solutions will be prescribed to the 55 ml / kg. Once before and one hour after administration of the solution, blood samples will be taken from three g

Eligibility

Sex/Gender

All

Age

15 Years to 70 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria; patients weighing more than 40 kg; Patients undergoing upper or lower limbs surgeries under general anesthesia or regional. Exclusion criteria: Patients received solutions other than standard maintenance solutions prior to the induction of anesthesia; Nonsteroidal anti-inflammatory drug use; taking any anticoagulant medications; Patients who have more than 100 cc of blood loss during the test period.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Clot firmness after 10 minutes. Timepoint: Before and one hour after administration of solutions. Method of measurement: by Thromboelastometer.;Clot formation time. Timepoint: Before and one hour after administration of solutions. Method of measurement: by Thromboelastometer.	—

Secondary

Measure	Time frame
Side effects. Timepoint: during and after surgery. Method of measurement: Physical examination.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFarsad Imani

Tehran University of Medical Sciences

imanifar@tums.ac.ir+98 21 63120

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026