Early cognitive function after Sevoflorane and Propofol anesthesia in 55-65 years old patients

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2012102211209N1

Enrollment

Registered

2013-02-02

Start date

2012-10-29

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cognitive disorder. disorders of psychological development

Interventions

Intervention 1: Propofol 100-200 micrograms / kg / minute during the 1-3 hour surgery. Intervention 2: During a 1-3 hour surgery with sevoflurane MAC1.

Treatment - Drugs

Propofol 100-200 micrograms / kg / minute during the 1-3 hour surgery

During a 1-3 hour surgery with sevoflurane MAC1

Eligibility

Sex/Gender

All

Age

55 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: patients needs elective abdominal Hernia surgery with ASA class 1 and 2 longed 1 to 4 hours. exclusion criteria:patients with emergency surgery ; ASA class 3 and 4;history of known Psychology;History of cardiovascular disease;Stroke; High intracranial pressure; Traumatic brain injury in the past 12 months; Addiction to Alcohol; Substance Abuse; Sensitivity to anesthetic drugs And unwillingness to participate in the study

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Attention. Timepoint: 48-24-12 hours later, 12 hours before anesthesia. Method of measurement: MMSE TEST.;Perception. Timepoint: 48-24-12 hours later, 12 hours before anesthesia. Method of measurement: MMSE TEST.;Speech. Timepoint: 48-24-12 hours later, 12 hours before anesthesia. Method of measurement: MMSE TEST.;Memory. Timepoint: 48-24-12 hours later, 12 hours before anesthesia. Method of measurement: MMSE TEST.;Learning. Timepoint: 48-24-12 hours later, 12 hours before anesthesia. Method of measurement: MMSE TEST.;Abstract thinking. Timepoint: 48-24-12 hours later, 12 hours before anesthesia. Method of measurement: MMSE TEST.	—

Measure

Time frame

Attention. Timepoint: 48-24-12 hours later, 12 hours before anesthesia. Method of measurement: MMSE TEST.;Perception. Timepoint: 48-24-12 hours later, 12 hours before anesthesia. Method of measurement: MMSE TEST.;Speech. Timepoint: 48-24-12 hours later, 12 hours before anesthesia. Method of measurement: MMSE TEST.;Memory. Timepoint: 48-24-12 hours later, 12 hours before anesthesia. Method of measurement: MMSE TEST.;Learning. Timepoint: 48-24-12 hours later, 12 hours before anesthesia. Method of measurement: MMSE TEST.;Abstract thinking. Timepoint: 48-24-12 hours later, 12 hours before anesthesia. Method of measurement: MMSE TEST.

—

Secondary

Measure	Time frame
Delirium. Timepoint: 48-24-12 hours later, 12 hours before anesthesia. Method of measurement: MMSE TEST.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr.Parviz Kheirkhah

Kashan Univercity Of Medical Sciences

parvizkheirkhah@yahoo.com+98 36 1533 0527

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026