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Therapeutic effects of Prolotherapy in patients with moderate knee osteoarthiritis

Therapeutic effects of Prolotherapy with intraarticular injection of dextrose solution in patients with moderate knee osteoarthiritis-a prelimminary intrventional pilot study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201210213217N4
Enrollment
20
Registered
2012-10-24
Start date
2012-10-26
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Primary gonarthrosis, bilateral. Primary gonarthrosis, bilateral

Interventions

Interaarticular injection of 7c.c dexterose 20% plus 2% lidocaine 1% with inferomedial approach in each injection time. For each patient three interaarticular injection in the manner of time 0 , time
Treatment - Drugs
Interaarticular injection of 7c.c dexterose 20% plus 2% lidocaine 1% with inferomedial approach in each injection time. For each patient three interaarticular injection in the manner of time 0 , time

Sponsors

Physical medicine and rehabilitation researches center
Lead Sponsor
Research chancellor of Tabriz University of medical sciences
Collaborator

Eligibility

Sex/Gender
All
Age
45 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1- Moderate knee osteoarthritis (grade 2 or 3 based on knee radiographic classification of kellgeren and Lawrence ) 2-No history of inflamatory Rheumatologic disease such as RA 3-Patient in the range of 45-75 years old 4-No reception of systemic or IV corticosteroid in two weeks before treatment and along treatment 5-Satisfactory of patients involved in study 6- NO response to conservative and physiotherapic treatments during 3 past month

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Intensity of pain. Timepoint: Before intervention and one month , two month ,three month and six month after intervention. Method of measurement: Using VAS grading score.

Secondary

MeasureTime frame
Knee range of motion. Timepoint: Before intervention and one month , two month ,three month and six month after intervention. Method of measurement: Using goniometer.;Daily functional ability. Timepoint: Before intervention and one month , two month ,three month and six month after intervention. Method of measurement: Using WOMAC questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactBahman Amouzandeh

Tabriz University of Medical Science

bahman.amouzandeh@yahoo.com+98 41 1337 3967

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026