post surgical pain. Follow-up care involving plastic surgery of head and neck
Conditions
Interventions
Intervention 1: Intervention: Tab Celecoxib 200 mg, 30min before operation, every 12 hour in first 24 hours. Intervention 2: Control group: Tab Acetaminophen 500 mg, 30 min before operation, every 6 h
Treatment - Drugs
Intervention: Tab Celecoxib 200 mg, 30min before operation, every 12 hour in first 24 hours
Control group: Tab Acetaminophen 500 mg, 30 min before operation, every 6 hour in first 24 hours
Sponsors
Vice Chancellor for Research of Shahid Beheshti University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: functional class I; completed informed consent form Exclusion criteria: history of allergy to acetaminophen or sulfonamides; unwillingness to participate in the study; complications of rhinoplastic surgery; severe drugs side effects; current sever illnesses such as: cardiovascular disease, diabetes mellitus type1, obstructive pulmonary disease and asthma, sever HTN, epilepsy, renal or liver dysfunction, analgesic consumption 12 hours before the surgery, alcohol or drug addiction.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain severity. Timepoint: before operation, 2hours after rhinoplasty, every 6 hour till 24 hours. Method of measurement: Visual Analogue Scale(VAS).;Requested analgesic dose. Timepoint: first 24 hours. Method of measurement: mg. | — |
Secondary
| Measure | Time frame |
|---|---|
| Surgical site bleeding. Timepoint: first 24 hours. Method of measurement: Observation. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAtena Esmaeli
Pharmacy School of Shahid Beheshti University of Medical Sciences
Outcome results
None listed