Comparing the effect of single dose of rectal Indomethacin and oral Melatonin on prevention of post ERCP pancreatitis

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

IRCT

Registry ID

IRCT20121021011192N6

Enrollment

200

Registered

2018-08-02

Start date

2017-08-24

Completion date

Unknown

Last updated

2018-09-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pancreatitis. Acute pancreatitis

Interventions

Intervention group 1: Receiving indomethacin suppository 100 mg just before doing Endoscopic Retrograde Cholangiopancreatography and Intervention group 2: Receiving melatonin tablet 3 mg just before d

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Patients undergoing ERCP in Taleghani hospital by taking written consen

Exclusion criteria

Exclusion criteria: Patients history of hypersensitivity against each of melatonin, indomethacin or diclofenac Active peptic ulcer diseases Renal impairment (GFR < 10 ml/min)

Design outcomes

Primary

Measure	Time frame
Occurrence of pancreatitis. Timepoint: 10 days after intervention. Method of measurement: Clinical evaluation.	—

Countries

Iran (Islamic Republic of)

Contacts

Public Contactnima naderi

Shahid Beheshti University of Medical Sciences

naderi@sbmu.ac.ir00

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026