Condition 1: Peptic ulcer due to Helicobacter pylori infection. Condition 2: Positive histopathological test for Helicobacter pylori infection. Peptic ulcer, site unspecified Helicobacter pylori [H. pylori] as the cause of diseases classified elsewhere
Conditions
Interventions
Intervention 1: Intervention group: patients receiving omeprazole 20 mg twice daily, metronidazole 500 mg twice daily, amoxicillin 1 g twice daily, bismuth subcitrate 240 mg twice daily, and Jiragastr
Sponsors
Shahid Beheshti University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Peptic ulcer confirmed through esophagogastroduodenoscopy (EGD) by a gastroenterology specialist Positive Helicobacter pylori histopathology
Exclusion criteria
Exclusion criteria: Renal or hepatic failure Pregnancy and breastfeeding
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Helicobacter pylori eradication status. Timepoint: 2 weeks after completion of the 8-week medication regimen. Method of measurement: Helicobacter pylori stool antigen test. | — |
Secondary
| Measure | Time frame |
|---|---|
| Occurrence rate of adverse drug reactions. Timepoint: At the end of week 2 of Helicobacter pylori eradication regimen. Method of measurement: Interview with the patients. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMohammad Abbasinazari
Shahid Beheshti University of Medical Sciences
Outcome results
None listed