A comparison between general anesthesia versus dissociative conscious sedation in hemodynamic responses to endobronchial intubation.

A comparison between general anesthesia versus dissociative conscious sedation_ subcutaneous ketamin+ intravenous narcotics_ in hemodynamic responses to endobronchial intubation in imam khomaini hospital, on 1391

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT201210209660N3

Enrollment

Registered

2012-11-25

Start date

2011-12-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mental and behavioural disorders due to use of sedatives or hypnotics. Mental and behavioural disorders due to use of sedatives or hypnotics

Interventions

Intervention 1: First group will receive 1-3 microgram/kg fentanyl + 0.1micro/kg morphine and 1mg midazolam as premedication and 5mg/kg thiopental plus 0.6mg/kg atracurium. Intervention 2: The second

Treatment - Drugs

First group will receive 1-3 microgram/kg fentanyl + 0.1micro/kg morphine and 1mg midazolam as premedication and 5mg/kg thiopental plus 0.6mg/kg atracurium.

The second group will receive 1-3microgram/kg fentanyl + 0.1micro/kg morphine and 1mg midazolam as premedication and 0.6mg/kg subcutaneous ketamine. The site of SQ injection is in front of the fore ar

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: all patients in ASA class 1 or 2 (without underlying disease or with mild underlying disease which is well controlled by medication) undergoing colonoscopy; age between 18-60. Exclusion criteria: any uncontrolled or poor controlled underlying disease; seizure disorders; history of hypersensitivity to egg or any drug; addiction to narcotics; mental retardation or any cognitive disorder.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
SPO2. Timepoint: Continuous. Method of measurement: pulse oxiometery.;Blood pressure. Timepoint: every 5 minutes. Method of measurement: noninvasive cuff measurrment.;Heart rate. Timepoint: every 5 minutes. Method of measurement: pulse counting.	—

Secondary

Measure	Time frame
Apnea. Timepoint: continuous. Method of measurement: observation.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSanaz Sha`bani

Tehran University of Medical Sciences

sanazshaabani@yahoo.com+98 21 61190

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026