Evaluation of fluvoxamine effect on tinnitus

The clinical trial of comparing the effect of fluvoxamine with placebo on intensity of tinnitus due to sensorineural hearing loss

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT2012101811157N1

Enrollment

100

Registered

2012-11-25

Start date

2012-09-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tinnitus. Tinnitus

Interventions

Intervention 1: Intervention/ Control1: Fluvoxamine group: Fluvoxamine / Oral Tablet 50 mg / Once a day for one month / Sobhan Company. Intervention 2: Intervention/Control2: Control group: Placebo c

Treatment - Drugs

Placebo

Intervention/ Control1: Fluvoxamine group: Fluvoxamine / Oral Tablet 50 mg / Once a day for one month / Sobhan Company

Intervention/Control2: Control group: Placebo capsule consisted of corn starch / 250 mg / Oral / Once a day for one month

Eligibility

Sex/Gender

All

Age

20 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: The patients who suffer from sensorineural hearing loss and tinnitus / No contraindication to fluvoxamine /With a written consent form Exclusion criteria: Using similar drugs / Using other medications that interact with fluvoxamine / Fluvoxamine side effects presentation

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Intensity of tinnitus. Timepoint: Before and one month after intervention. Method of measurement: According to Tinnitus Matching.	—

Secondary

Measure	Time frame
Frequency of tinnitus. Timepoint: Before and one month after intervention. Method of measurement: According to Tinnitus Matching.;Sex. Timepoint: Before intervention. Method of measurement: According to questionnaire.;Tone of tinnitus. Timepoint: Before and one month after intervention. Method of measurement: According to Tinnitus Matching.;Age. Timepoint: Before intervention. Method of measurement: According to questionnaire.;The satisfaction of treatment. Timepoint: After intervention. Method of measurement: According to Visual Analog Scale.	—

Measure

Time frame

Frequency of tinnitus. Timepoint: Before and one month after intervention. Method of measurement: According to Tinnitus Matching.;Sex. Timepoint: Before intervention. Method of measurement: According to questionnaire.;Tone of tinnitus. Timepoint: Before and one month after intervention. Method of measurement: According to Tinnitus Matching.;Age. Timepoint: Before intervention. Method of measurement: According to questionnaire.;The satisfaction of treatment. Timepoint: After intervention. Method of measurement: According to Visual Analog Scale.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Siroos Kazemi

Lorestan University of Medical Sciences

Drkazemi@lums.ac.ir+98 6616200155169

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026