Major Depressive Disorder. Recurrent Depressive Disorder
Conditions
Interventions
Intervention 1: In one group Mirtazapin 15-30 mg .once a day, 8 week. Intervention 2: In one group Citalopram 20-40mg, twice a day,8 week.
Treatment - Drugs
In one group Mirtazapin 15-30 mg .once a day, 8 week
In one group Citalopram 20-40mg, twice a day,8 week
Sponsors
University of Social Welfare and Rehabilitation Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria:Diagnosis of Major Depressive Disorder by DSM-IV and anxiety symptoms by Beck Anxiety Rating Scale ( at least 16) and Hamilton Anxiety Rating Scale (at least 13);Age between 18 -65 years old;lack of phisical disorder. Exclusion criteria: History of bipolar disorder or schizoaffective ; Suicide or homicide risk; Contraindication for psychiatric medicine;ECT in the last month;Substance abuse;Pregnancy;Breastfeeding;Planning a pregnancy in female;Psychosis
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Depression. Timepoint: In week 0,2,4,8. Method of measurement: Hamilton and Beck Depression Scale.;Anxiety. Timepoint: in week 0,2,4,8. Method of measurement: hamilton and beck anxiety scale. | — |
Secondary
| Measure | Time frame |
|---|---|
| Side effect. Timepoint: in week 2,4,8. Method of measurement: check list according to the reference. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public Contactkamelya Goudarzi
University of Social Welfare and Rehabilitation Sciences
Outcome results
None listed