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Effect of intranasal Desmopressin in renal colic pain management

Comparison between intranasal Desmopressin and intravenous Acetaminophen in renal colic pain management

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2012101510017N4
Enrollment
300
Registered
2013-04-29
Start date
2012-03-19
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Renal colic. Unspecified renal colic

Interventions

Intervention 1: Control group: 15 mg/kg of intravenous Acetaminophen with maximum dose of 1000 mg as a single dose. Intervention 2: Intervention group: 40 micro gr of intranasal desmopressin as a sing
Treatment - Drugs
Control group: 15 mg/kg of intravenous Acetaminophen with maximum dose of 1000 mg as a single dose.
Intervention group: 40 micro gr of intranasal desmopressin as a single dose.

Sponsors

Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
15 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion criterion: patients with renal colic impression on diagnosis. Exclusion criteria: patients for whom another diagnosis would be established rather than renal colic; analgesic use 4 hours before admission; opium addiction; any kind of renal, hepatic or infectious disease; pregnancy.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Pain severity. Timepoint: Before intervention and 15, 30, 60 min after intervention. Method of measurement: Visual analog pain scale.

Secondary

MeasureTime frame
Final mortality and morbidity. Timepoint: 24 hours and one week after intervention. Method of measurement: Asking by phone.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Hamed Basir Ghafouri

Tehran University of Medical Science, School of Medicine

h-basirghafouri@tums.ac.ir+98 21 6652 5327

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026