acute pain in critical limb ischemia. Arterial embolism and thrombosis
Conditions
Interventions
Intervention 1: Intravenous infusion of Lidocaine 2mg/kg
at the rate of 5cc/min with
close cardiac monitoring
in the control group. Intervention 2: Intravenous infusion of Morphine 0.1 mg/kg
a
Treatment - Drugs
Intravenous infusion of Lidocaine 2mg/kg
at the rate of 5cc/min with
close cardiac monitoring
in the control group
Intravenous infusion of Morphine 0.1 mg/kg
at the rate of 5cc/min
with close cardiac monitoring
in the case group
Sponsors
Tehran University of Medical Sciences -Faculty of Medicine
Eligibility
Sex/Gender
All
Age
15 Years to No maximum
Inclusion criteria
Inclusion criteria: Inclusion Criteria: having clinical signs and symptoms of acute critical limb ischemia which are known with 5P (Pain-paralysis – pulselessness- paresthesia- pallor) and is diagnosed by an emergency medicine specialist. Consent to join in the study is required and the form is read and signed by each one of the patients. Exclusion criteria: contraindications of lidocaine and morphine: lung problems (including acute asthma; pulmonary edema); Heart conditions(including heart failure; cardiogenic shock; Block degree three; arrhythmia WPW and Stoke Adams syndrome); neurological problems(including seizures; changes in state of consciousness); chronic pain in another site; pregnancy; use of pain killers in recent week; allergy to lidocaine or morphine; addiction; prescription of opioid drugs intravenously by EMS or triage nurses; respiratory distress; blood pressure <100mmhg; trauma; altered level of consciousness; language problems and dementia.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain scoring. Timepoint: 0-15-30 Min after the begining of study. Method of measurement: visual analogue scale. | — |
Secondary
| Measure | Time frame |
|---|---|
| Side effect. Timepoint: 0-15-30 min after the begining of study. Method of measurement: by name.;Blood pressure. Timepoint: 0-15-30 min after the begining of study. Method of measurement: mm/hg.;Heart rate. Timepoint: 0-15-30 min after the begining of study. Method of measurement: beats per min.;Pulse oximetry. Timepoint: 0-15-30 min after the begining of study. Method of measurement: %. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Elnaz vahidi
Tehran University of Medical Sciences-Faculty of Medicine emergency departement
Outcome results
None listed