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Evaluation of Adverse early Outcomes of Prolonged Initial Empirical Antibiotic Therapy in Premature Infants

Evaluation of Adverse early Outcomes of Prolonged Initial Empirical Antibiotic Therapy in VLBW Premature Infants

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201210124113N3
Enrollment
150
Registered
2014-04-24
Start date
2013-11-01
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Very Low Birth Weight infants. Other low birth weight

Interventions

Intervention 1: In Control group after starting the empirical Antibiotics at the time of admission they will be continued until the patients have Iv access. Intervention 2: in case group after st
Treatment - Drugs
In Control group after starting the empirical Antibiotics at the time of admission they will be continued until the patients have Iv access
in case group after starting the empirical Antibiotics at the time of admission they will be discontinued after 3-5 days if the results of B/C and CRP would be negative and clinical condition woul

Sponsors

Pediatric Health Research center of Tabriz University of Medical Sceinces
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 1 Years

Inclusion criteria

Inclusion criteria: Inborn preterm infants in Alzahra Teaching hospital of Tabriz Without congenital Anomaleis Very Low Birth weight ( VLBW): Birth Weight 1499 and less Admit in 72 hours of life for respiratory Distress or R/O Sepsis

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Nosocomial Infection. Timepoint: from 72 hours of life until Discharge. Method of measurement: Positive blood culture with clinical symptoms.;Mortality. Timepoint: From admision time until discharge or death time. Method of measurement: Evaluation ang registration form of hospital.;Necrotizing Entrocolitis ( stage 2 or more). Timepoint: after the day 5 until discharge. Method of measurement: gastrointestinal symptoms and radiologic evidence.

Secondary

MeasureTime frame
Duration of hospitalization. Timepoint: from the admition time until discharge. Method of measurement: Registration Form( Medical records of the patient ).;Total days of Antibiotic therapy. Timepoint: From the first day of admission until discharge. Method of measurement: Registration form ( Medical records of the patient as days ).;Chronic Lung Disease. Timepoint: Need of Oxygen or Respiratory support more than 28 days after birth. Method of measurement: Registration form(Medical records of the patient).;Intraventricular Hemorrage ( Grade 2 or more ). Timepoint: 7-10 days after birth. Method of measurement: Brain Sonography.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Mohammad Bagher Hosseini

Tabriz University Of Medical Sceinces

hosseini_mb@yahoo.com+98 41 1335 0357

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026