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Effect of probiotics on pathogenic bacteria in the stomach seminars adult patients undergoing mechanical ventilation in the intensive care unit, a clinical trial

Effect of probiotics on pathogenic bacteria in the stomach seminars adult patients undergoing mechanical ventilation in the intensive care unit, a clinical trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2012101211091N1
Enrollment
68
Registered
2015-01-28
Start date
2013-09-01
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ventilator Assosiated Pneumonia. Bacterial Pneumonia not Elsewhere Classified

Interventions

Intervention 1: Prescribe1 capsule of probiotics (lactocare)which contains 6.18 ×?10?^10 coloni of seven probiotics. Intervention 2: 1 capsule of placebo. Intervention 3: Take a throat culture in the
Treatment - Drugs
Placebo
Diagnosis
Prescribe1 capsule of probiotics (lactocare)which contains 6.18 ×?10?^10 coloni of seven probiotics.
1 capsule of placebo
Take a throat culture in the fourth and sixth day after the first culture

Sponsors

Vice Chancellor for Research, Shiraz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Inclusion criteria: at least 18 years; the consent of the relatives; unconscious patients with endotracheal tube and under mechanical ventilation; probability of 95% for continuing these circumstances within the next six days; patients within 24 hours of abolished the NPO. Exclusion criteria: pregnancy; weakened immune system due to any reason (HIV, leukemia; lupus; donors receive a suppressed immune systems; heart valve replacement; eclipses, vascular; cardiac trauma; history of rheumatic fever; endocarditis; congenital heart anomalies; injuries of stomach; esophagus or intestine; airway injuries; tracheostomy; pancreatitis.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
To determine the bacteria in the throat. Timepoint: from arrival to the ICU untill 24 hours. Method of measurement: Colonies Count.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMajid Yazdani

Shiraz University of Medical Sciences

yazdanimajid70@yahoo.com+98 71 1629 1470

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026