Anesthesia. Injuries to the knee and lower leg
Conditions
Interventions
Intervention 1: Intervation group received oral mexiletine 200 mg 2 hours before operation. Intervention 2: Control group ricieved multivitamin capsul 2 hours before operation.
Treatment - Drugs
Intervation group received oral mexiletine 200 mg 2 hours before operation
Control group ricieved multivitamin capsul 2 hours before operation
Sponsors
Kerman University of Medical Science( Research and Technology center)
Eligibility
Sex/Gender
All
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria;Elective lower limb surgery; Age 18-51years;Height 150-190cm; Weight 50-90kg;ASA 1,2 Exclusion criteria; ??Alchohole or narcotic drug consumption;Psychological disorders;Allergic reaction with lidocaine;Infection wound ;Open lower limb fracture;Liver disease;Bradycardia;Cardiac block;Seizure;Recieve analgesic or opiuom before operation .
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Duration time of sensory block. Timepoint: Every 10 min. Method of measurement: The onset time from not sensing pin prick at T10 dermatom until two dermatoms regression from T10.;Duration time of motor block. Timepoint: Every 10 min. Method of measurement: The onset time from unabling to elevate knee until flexion of leg. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Sharifzadeh Mahdieh
Kerman University of Medical science
Outcome results
None listed