Factors affecting the outcome of Lumbosacral Spinal Surgery

Evaluating the effect of Acetazolamide adminestration and prone positioning following lumbosacral spinal surgery in preventing cerebro spinal fluid leak and collection and wound dehissence

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2012100611023N1

Enrollment

144

Registered

2013-04-24

Start date

2012-09-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Tethered cord- split cord malformation. Condition 2: Lipomyelomeningocele. Disorder of brain, unspecified Benign lipomatous neoplasm, unspecified

Interventions

Intervention 1: Group A: Acetazolamide administration (as tablet or solved in water, dosage depending on the weight of the child) for 10 days. Intervention 2: Group C: Acetazolamide administration(as

Prevention

Group A: Acetazolamide administration (as tablet or solved in water, dosage depending on the weight of the child) for 10 days

Group C: Acetazolamide administration(as tablet or solved in water, dosage depending on the weight of the child) for 10 days+ prone positioning for 10 days

Group B: prone positioning for 10 days

Group D: no intervention

Eligibility

Sex/Gender

All

Age

No minimum to 18 Years

Inclusion criteria

Inclusion criteria: The patients visiting the neurosurgery clinic of children`s medical center hospital during Autumn 2012 to the end of winter of 2015 who need lumbosacral surgery will be screened. If these patients underwent unthetering surgery due to primary tethered cord syndrome, resection of lipoma, lipomyelomeningocele, split cord malformation management, tumors with intradural management or having any other disease with similar management technique due to the opinion of the surgeon, they will be included. Patients with diagnosis of myelomeningocele, meningocele, infected dermoid cysts, intramedullary abscess, presence of hydrocephalus and those who underwernt reoperation will be excluded from this study.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Cerebrospinal fluid leakage. Timepoint: 1month. Method of measurement: specialist opinion.;Cerebrospinal fluid collection. Timepoint: 1 month. Method of measurement: specialist opinion.;Wound dehiscence. Timepoint: 1 month. Method of measurement: specialist opinion.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactShima Shahjouei

Tehran University of Medical Sciences

shimashah@student.tums.ac.ir+98 21 8825 6697

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026