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Comparison of intravenous mannitol and acetaminophen caffeine in postural headache after cesarean section

Comparison of intravenous mannitol and oral acetaminophen caffeine in treatment of post dural puncture headache after cesarean section by spinal anesthesia

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20121006011020N12
Enrollment
80
Registered
2019-02-19
Start date
2018-11-23
Completion date
Unknown
Last updated
2019-02-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post dural puncture headache. Spinal and epidural anesthesia-induced headache during labor and delivery

Interventions

Intervention 1: Intervention group: 500 ml of intravenous mannitol in 20% solution will be infused over half an hour. Intervention 2: Intervention group: Acetaminophen caffeine tablets (containing ac

Sponsors

Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 36 Years

Inclusion criteria

Inclusion criteria: ASA class I,II Age range 18-36 years Patient with headache that occur within 72 hours after cesarean section with headache criteria due to spinal anesthesia

Exclusion criteria

Exclusion criteria: Migraine headache or chronic headache History of medical condition including heart disease, kidney disease, diabetes history, high blood pressure Pre-eclampsia, Eclampsia Any disorder of the central nervous system and seizures Sedative use twenty-four hours before surgery drug or alcohol user

Design outcomes

Primary

MeasureTime frame
Headache condition. Timepoint: Before and within 24 hours after treatment. Method of measurement: Visual analog scale.;Patient Satisfaction. Timepoint: After 24 Hours of intervention. Method of measurement: Questionnaire.;Drug side effects. Timepoint: Within 24 Hours of intervention. Method of measurement: Questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSepideh Salehi Vaziri

Tehran University of Medical Sciences

spdsvaziri@gmail.com+98 21 7771 9922

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026