Neonatal jaundice. P59.9 Neonatal jaundice, unspecified
Conditions
Interventions
Intervention 1: control group receiving only phototherapy. Intervention 2: intervention group 1 receiving a single low dose of oral clofibrate (25 mg/kg) plus phototherapy. Intervention 3: interventi
Treatment - Drugs
control group receiving only phototherapy
intervention group 1 receiving a single low dose of oral clofibrate (25 mg/kg) plus phototherapy
intervention group 2 receiving a single moderate dose of oral clofibrate (50 mg/kg) plus phototherapy.
Sponsors
Hamadan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
1 Years to 1 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria included: (a) age of 2 to 29 days; (b) full term newborn (gestational age between 38 to 40 weeks); (c) weight of 2500 to 4000 gr; having indirect hyperbilirubinemia (TSB>16 mg/dl) ; (d) absence of hemolysis, ABO or Rh incompatibility; (e) negative coomb’s test; (f) reticulocyte count less than 5%. Exclusion criteria : The neonates with sign of sepsis, electrolyte impairment, any congenital anomalies or disease, seizure, formula feeding, hemolytic disease and those who need exchange transfusion were excluded from the study.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bilirubin. Timepoint: Total and indirect bilirubin levels were measured at the beginning of treatment and then 12, 24, 36 and 48 hours later. Method of measurement: RA1000 Techinca. | — |
Secondary
| Measure | Time frame |
|---|---|
| Bilirubin. Timepoint: Total and indirect bilirubin levels were measured at the beginning of treatment and then 12, 24, 36 and 48 hours later. Method of measurement: RA1000 Techinca. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Fatemeh Eghbalian
Hamadan University of Medical Siences
Outcome results
None listed