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Heated Humidified High Flow Nasal Cannula and RDS recovery in newborns

A comparison of 2 interventions for the Heated Humidified High Flow Nasal Cannula (HHHFNC) in preterm infants weighing 1000g to 1500g in the recovery period from newborns Respiratory Distress Syndrome (RDS)

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2012092410430N3
Enrollment
70
Registered
2013-05-24
Start date
2012-09-22
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Newborn RDS. Respiratory distress of newborn

Interventions

Intervention 1: Intervention Group: • For the newborns in the 7000PMH group the same procedure was applied except for the humidifying system for which the relative humidity and the temperature were s
first of all appropriate nasal cannula was provided which its diameter was not more than 50% of the newborn's nostril (11). Then the nasal cannula was attached to the specific circuit and was linked
Treatment - Devices
Intervention Group: • For the newborns in the 7000PMH group the same procedure was applied except for the humidifying system for which the relative humidity and the temperature were set to 100% and
Control Group: For the MR850 group newborns

Sponsors

Esfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
1 Years to 30 Years

Inclusion criteria

Inclusion criteria: Newborns receiving surfactant due to affiliation with RDS and their oxygen saturation was equal or more than 90% under nCPAP with CDP=4 cm H2O and FiO2<30% during the last 4 hrs, who still needed oxygen supplement after disconnection from nCPAP were included in the study; the exclusion criteria for this study were if there was a congenital malformation; prenatal asphyxia (min 5 apgar score equals 0 to 3, or umbilical cord pH less than 7, and the Bicarbonate level of the umbilical cord was reported to be less than 12), or nasal mucosa erythematic.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Humidity. Timepoint: Every 6 hours. Method of measurement: Hygrometer.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAlireza Sadeghnia

Esfahan University of Medical Sciences

sadeghnia@med.mui.ac.ir+98 915 316 7951

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026