Other and unspecified disorders of circulatory system. Other and unspecified disorders of circulatory system
Conditions
Interventions
Intervention 1: Patients in group one received a 20mg/kg bolus dose of magnesium sulphate over a period of 3 minutes followed by an infusion of magnesium sulphate10 mg/kg/hour. Intervention 2: Patient
Prevention
Treatment - Drugs
Patients in group one received a 20mg/kg bolus dose of magnesium sulphate over a period of 3 minutes followed by an infusion of magnesium sulphate10 mg/kg/hour
Patients in group two received a 40mg/kg bolus dose of magnesium sulphate over a period of 3 minutes followed by an infusion of magnesium sulphate(20 mg/kg/hour).
Patients in group three received saline as placebo for bolus and infusion.
Sponsors
Vice chancellor of research-Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
40 Years to 80 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Patients refered to our anesthesia clinic; Patients aged 40 to 80 years undergoing Coronary Artery Bypass Graft Surgery Exclusion Criteria:Patients with left ventricular ejection fraction less than 40% ; left ventricular aneurysm;valvular heart disease; previously documented hypertension; diabetes mellitus
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Heart rate during intubation. Timepoint: Before intubation and 2 and 4 minutes after intubation. Method of measurement: Using patients monitoring.;Heart rate during sternotomy. Timepoint: Before sternotomy and 2 and 4 minutes after. Method of measurement: Using patients monitoring. | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood pressure during intubation. Timepoint: Before intubation and 2 and 4 minutes after. Method of measurement: Using sphygmomanometer.;Blood pressure during sternotomy. Timepoint: Before sternotomy and 2 and 4 minutes after. Method of measurement: Using sphygmomanometer. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Omid Azimaraghi
Dr Shariati Hospital
Outcome results
None listed