The effect of herbal mixture extract on endometrial histology in patients with disordered simple hyperplasia.

The effect of herbal mixture extract on endometrial histology in patients with disordered proliferative endometrium and simple hyperplasia.

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20120922010901N9

Enrollment

Registered

2022-01-16

Start date

2022-01-10

Completion date

Unknown

Last updated

2022-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

malignant neoplasm of female genital organs. malignant neoplasm of female genital organs

Interventions

Intervention 1: Intervention group: Intervention group will consume Megestrol Acetate (40 mg) daily along with a medicinal herb mixture (500 mg) daily for three months. Intervention 2: Control group:P

Eligibility

Sex/Gender

Female

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Women with abnormal uterine bleeding and proliferative endometrium with irregular glands Willingness to participate in the study Lack of sensitivity to the plants used in the study

Exclusion criteria

Exclusion criteria: Thromboembolism Severe liver dysfunction High blood pressure

Design outcomes

Primary

Measure	Time frame
Endometrial histology. Timepoint: Before intervention, three months after intervention. Method of measurement: Endometrial biopsy.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Parvin Mostafa Gharabaghi

Tabriz University of Medical Sciences

gharabagh.p@tbzmed.ac.ir+98 41 1553 9161

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026