postoperative pain. Other acute postprocedural pain
Conditions
Interventions
Intervention 1: Intervention group: two hours prior to surgery, patients in this group receive 60 mg oral capsule of duloxetine
brand name of Loxeta, made by Abidi pharmaceutical company. Intervention 2: Control group: in this group, patients receive placebo.
Sponsors
Kerman University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: All patients admitted to Afzalipoor Hospital for hysterectomy surgery ASA classification of I (without systemic disease) and II (with controlled systemic disease) informed consent of patient for participation
Exclusion criteria
Exclusion criteria: long term usage of opioids steroid thrapy age less than 18 and more than 85 year pregnancy heart, hepatic and renal failure uncontrolled hypertension endocrine diseases BMI greater than 40 heart rate less than 50 evidence of heart block in ECG presence of suizure, epilepsy and bipolar disorders surgery lasting more than 3 hours huge bleeding during surgery
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative pain. Timepoint: The level of pain is measured and documented every 15 minutes after patient reorientation, until discharge from recovery room. Method of measurement: Visual Analogue Scale (VAS) is used for pain assessment. | — |
Secondary
| Measure | Time frame |
|---|---|
| Patient satisfaction. Timepoint: 24 hours after surgery. Method of measurement: postoperative quality of recovery (QOR) score.;Vital signs. Timepoint: every 15 minutes. Method of measurement: authomathic monitoring system. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFariba Mansoorinassab
Kerman University of Medical Sciences
Outcome results
None listed