The effect of method of anesthesia in decrease of signs of bone cement implantation syndrome

The effect of general anesthesia with etomidate for decrease of signs of bone cement implantation syndrome compare with spinal amesthesia in cemented hip arthroplasty

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2012091910882N1

Enrollment

160

Registered

2012-12-17

Start date

2012-10-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bone cement implantation syndrome. Fracture of bone following insertion of orthopaedic implant, joint prosthesis, or bone plate

Interventions

Intervention 1: Patients under general anesthesia after receiving 500 cc Ringer lactate are inducted with Midazolam (0.3 mg / kg), Fentanyl (2 micg / kg) and Etomidate (0.3 mg / kg). The patients are

Prevention

Patients under general anesthesia after receiving 500 cc Ringer lactate are inducted with Midazolam (0.3 mg / kg), Fentanyl (2 micg / kg) and Etomidate (0.3 mg / kg). The patients are intubated with C

Patients undergoing spinal anesthesia after receiving 500 cc Ringer lactate are placed in the sitting or lateral position. Bupivacaine (20 mg) is injected into the subarachnoid space with using a No.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Inclusion criteria: The patient are candidate for hip arthroplasty; and use cement for their sergury. A. S.A class I-III;HB>10 Exclusion criteria:The pateint be sensitive to etomidate and cement;hip arthroplasty without cement;A. S. A class IV;revesion of hip prothes

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Blood pressure. Timepoint: induction of anesthesia, before insertion of cement, 5 minute and 10 minute after cement. Method of measurement: barometer(mm hg).;Puls rate. Timepoint: induction of anesthesia, before insertion of cement, 5 minute and 10 minute after cement. Method of measurement: puls oximetre.;Arterial oxigen saturation. Timepoint: induction of anesthesia, before insertion of cement, 5 minute and 10 minute after cement. Method of measurement: puls oximetre.	—

Measure

Time frame

Blood pressure. Timepoint: induction of anesthesia, before insertion of cement, 5 minute and 10 minute after cement. Method of measurement: barometer(mm hg).;Puls rate. Timepoint: induction of anesthesia, before insertion of cement, 5 minute and 10 minute after cement. Method of measurement: puls oximetre.;Arterial oxigen saturation. Timepoint: induction of anesthesia, before insertion of cement, 5 minute and 10 minute after cement. Method of measurement: puls oximetre.

—

Secondary

Measure	Time frame
Cardiac arrest and death. Timepoint: any time after insertion of cement. Method of measurement: vital signs.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAli Iravani

kashan Univercity of Medical Sciences

dairavani@yahoo.com+98 35 1626 7752

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026