Effect of steroid on neonatal respiratory morbidity in elective cesarean section in 37 weeks or later

Assessment of effect of antenatal betamethasone administration on neonatal respiratory morbidity in early term (37 to 38 weeks and 6 days) elective cesarean section

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20120918010876N4

Enrollment

220

Registered

2018-01-11

Start date

2017-07-25

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Respiratory distress syndrome of newborn. Respiratory distress syndrome of newborn

Interventions

Intervention 1: Intervention group: intramuscular injection of 12 mg betamethasone in two doses between 24 hours, 48 hours before cesarean section. Intervention 2: Control group: No Treatment.

Treatment - Drugs

Intervention group: intramuscular injection of 12 mg betamethasone in two doses between 24 hours, 48 hours before cesarean section

Control group: No Treatment

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: referring women for early or 37 to 38 weeks and 6 days elective cesarean section singleton pregnancy

Exclusion criteria

Exclusion criteria: multiple pregnancies fetus with major congenital anomalies fetus with other medical or midwifery conditions that give birth earlier receive dexamethasone or betamethasone during pregnancy maternal severe hypertension maternal history of peptic ulcer evidences of intrauterine infection

Design outcomes

Primary

Measure	Time frame
Neonatal respiratory outcomes (need for CPAP or nasal cannula with high-current continuous, need for continuous high-pressure oxygen with FiO2 more than 30%, need for mechanical ventilation, need for ECMO or resuscitation at birth, respiratory distress syndrome, neonatal tachypnea, apnea, bronchopulmonary dysplasia, pneumonia, use of surfactant). Timepoint: After cesarean until patient discharge. Method of measurement: Clinical symptoms & signs.;NICU admission. Timepoint: After cesarean until patient discharge. Method of measurement: Clinical symptoms & signs.;Hospitalization duraion. Timepoint: Patient discharge. Method of measurement: Patient discharge in day and hour.	—

Measure

Time frame

Neonatal respiratory outcomes (need for CPAP or nasal cannula with high-current continuous, need for continuous high-pressure oxygen with FiO2 more than 30%, need for mechanical ventilation, need for ECMO or resuscitation at birth, respiratory distress syndrome, neonatal tachypnea, apnea, bronchopulmonary dysplasia, pneumonia, use of surfactant). Timepoint: After cesarean until patient discharge. Method of measurement: Clinical symptoms & signs.;NICU admission. Timepoint: After cesarean until patient discharge. Method of measurement: Clinical symptoms & signs.;Hospitalization duraion. Timepoint: Patient discharge. Method of measurement: Patient discharge in day and hour.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Masoome Mirzamoradi

Shahid Beheshti University of Medical Sciences- Mahdieh Hospital

drmoradi000@yahoo.com+98 21 5506 6263

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026