Respiratory distress syndrome of newborn. Respiratory distress syndrome of newborn
Conditions
Interventions
Intervention 1: Treatment group: intramuscular injection of 12 mg betamethasone in two doses between 24 hours. Intervention 2: Control group: No Treatment.
Treatment - Drugs
Treatment group: intramuscular injection of 12 mg betamethasone in two doses between 24 hours
Sponsors
Shahid Beheshti University of Medical Sciences- Mahdieh Hospital
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Singleton pregnancy Gestational age from 34 weeks and 0 days to 36 weeks and 6 days High probability of preterm labor (in weeks 37-34) due to premature rupture of membranes Preterm labor with intact membranes preterm labor with any indication (including previous cesarean section, intrauterine growth retardation (IUGR), Oligohydramnios, pre-eclampsia, etc.)
Exclusion criteria
Exclusion criteria: No exact gestational age (unknown firt day of last menstrual period (LMP) or no ultrasound dating) Cervix dilatation of 4 cm or more Planned delivery after 36 weeks and 6 days Known congenital malformations Received corticosteroids before week 34 or for other indications Fetal death Major fetal anomaly Non-viable fetus Gestational diabetes Diabetes before pregnancy Maternal contraindications for betamethasone Chorioamnionitis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Neonatal respiratory outcomes. Timepoint: After delivery until patient discharge. Method of measurement: Clinical symptoms & signs.;NICU admission. Timepoint: After delivery until patient discharge. Method of measurement: Clinical symptoms & signs.;Hospitalization duration. Timepoint: Patient discharge time. Method of measurement: Hospitalization duration in day and hour. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Masoome Mirzamoradi
Shahid Beheshti University of Medical Sciences- Mahdieh Hospital
Outcome results
None listed