Skip to content

Effect of clonidine on hemodynamic changes and bleeding

Effect of clonidine premedication on intraoperative Hemodynamic changes and Blood loss in mandibular fracture surgery .

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2012091610853N1
Enrollment
86
Registered
2012-10-09
Start date
2011-03-01
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fracture of mandible. Fracture of mandible

Interventions

Intervention 1: In treatment group 1. Clonidine mg given orally one hour before surgery. Blood pressure, heart rate and mean arterial pressure one hour before surgery and during the specified times fo
Treatment - Surgery
Treatment - Drugs
In treatment group 1. Clonidine mg given orally one hour before surgery. Blood pressure, heart rate and mean arterial pressure one hour before surgery and during the specified times for 10 minutes and
In the control group given a placebo an hour before surgery . Blood pressure, heart rate and mean arterial pressure one hour before surgery and during the specified times for 10 minutes and are reco

Sponsors

Vice-chancellor for research -Ahvaz Jondishapur University of Medical Science
Lead Sponsor

Eligibility

Sex/Gender
All
Age
15 Years to 35 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria : Groupings of men and women in the class I or II ASA; men and women between 15 to 35 years Exclusion criteria: Patients with a positive medical history of systemic diseases

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Blood loss and hemodynamic changes. Timepoint: preoperative and Intraoperative. Method of measurement: ml and mmH.g with manometer.

Secondary

MeasureTime frame
The consumption of morphine and fentanyl, and remifentanil. Timepoint: intraoperative. Method of measurement: Micro g/ kg and mg/ kg.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactOmid Ghasemzadeh

Ahvaz University of Medical Sciences

ghasemzadeho@yahoo.com+98 61 1372 7219

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026