ulcerative colitis. Ulcerative colitis, unspecified
Conditions
Interventions
Intervention 1: control group: placebo. Intervention 2: Intervention group: 500 mg/day resveratrol.
Placebo
Treatment - Other
control group: placebo
Intervention group: 500 mg/day resveratrol
Sponsors
National Nutrition and Food Technology Research Institute (NNFTRI)
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Age of 18 years and older; BMI between 18.5-30; histopathologic findings compatible with ulcerative colitis (mild-moderate active). Exclusion criteria: other enteral, autoimmune, inflammatory diseases and cancers; Pregnancy & Breast feeding, use of oral contraceptive drugs, using multivitamins, minerals, omega-3, poly phenolic and anti oxidant supplements in previous month, Use of drugs such as calcium channel blockers, NSAIDs, heparin ,varfarin and anti histamin in previous month; changes in dosage and kind of drugs in previous month and changes in dosage and kind of drugs during intervention; activation of disease resulting to hospitalization; reluctancy to continue.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Quality of life (IBDQ-9). Timepoint: at weeks: 0 and 6. Method of measurement: questionnarie.;Serum TNF-a. Timepoint: at weeks: 0 and 6. Method of measurement: ELISA.;Serum hs-CRP. Timepoint: at weeks: 0 and 6. Method of measurement: ELISA. | — |
Secondary
| Measure | Time frame |
|---|---|
| Weight and BMI. Timepoint: at weeks: 0 and 6. Method of measurement: Weight will be measured by Secca scale , BMI by formula.;Waist circumference, hip circumfereance. Timepoint: at weeks: 0 and 6. Method of measurement: non stretch meter.;Height. Timepoint: at weeks: 0 and 6. Method of measurement: non stretch meter. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAzita Hekmatdoost, MD, PhD
National Nutrition and Food Technology Research Institute (NNFTRI)
Outcome results
None listed