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Evaluation of Efficacy of intravenous magnesium sulphate with lidocaine 2% in preventing laryngospasm and postoperative pain after tonsilectomy

The comparative Evaluation of Efficacy of intravenous magnesium sulphate with lidocaine 2% in preventing laryngospasm and postoperative pain after tonsilectomy: Double blind clinlcal trial

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20120915010841N22
Enrollment
62
Registered
2020-01-24
Start date
2019-11-01
Completion date
Unknown
Last updated
2020-02-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

laryngospasm and complications after tonsilectomy. Laryngeal spasm

Interventions

Intervention 1: Intervention group: Children 3-14 years of age candidate for adenotonsillectomy will receive 15 mg / kg magnesium sulfate in a total volume of 15 ml two minutes after intubation. Inter

Sponsors

Hamedan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
3 Years to 14 Years

Inclusion criteria

Inclusion criteria: Age 3-14 years old with ASA Class 1 & 2 Candidate for elective adenotonsillectomy Parental consent to participate in the project

Exclusion criteria

Exclusion criteria: Heart, pulmonary and renal disease Recent infection of the upper respiratory tract and fever A history of allergies to magnesium sulfate, lidocaine Probability of intubation difficult Corticosteroid intake Arrhythmias and heart blocks A history of myasthenia gravis

Design outcomes

Primary

MeasureTime frame
Laryngospasm. Timepoint: 1, 5, 10 and 15 minutes after extubation. Method of measurement: Observation.

Secondary

MeasureTime frame
Nausea & vomiting. Timepoint: After surgery. Method of measurement: Observation.;Systolic and Diastolic Blood Pressure. Timepoint: Every two minutes for 10 minutes and then every 10 minutes to 60 minute. Method of measurement: Non-invasive automatic barometric device.;Heart Rate. Timepoint: Every two minutes for 10 minutes and then every 10 minutes to 60 minute. Method of measurement: Non-invasive automatic barometric device.;Sedation. Timepoint: We record ramsy sedation score in 24 hours after surgery.?. Method of measurement: Ramsy sedation score.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNahid Manouchehrian

Hamedan University of Medical Sciences

manuchehriann@gmail.com+98 81 3827 7012

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026