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Evaluation of intravenous Propofol and Midazolam on sedation during spinal anesthesia in cesarean section

Comparative Evaluation of intravenous Propofol and Midazolam on sedation and nausea & vomiting during spinal anesthesia in cesarean section

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20120915010841N21
Enrollment
102
Registered
2019-11-14
Start date
2019-10-22
Completion date
Unknown
Last updated
2019-12-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

sedation and nausea & vomiting during spinal anesthesia in cesarean section. Failed moderate sedation during procedure

Interventions

Intervention 1: Intervention group: : The amount of 0.2 mg/kg Propofol 1%(10mg/ml and made by B.BRAUN company in Germany), is injected intravenously after spinal anesthesia by anesthesiologist. Interv

Sponsors

Hamedan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 46 Years

Inclusion criteria

Inclusion criteria: 18-45 aged pregnant women for C/S ASA CLASS 1, 2 Satisfaction to participate in the project Pregnant women who underwent cesarean section under spinal anesthesia

Exclusion criteria

Exclusion criteria: sensitivity to medications used Patients who have failed spinal anesthesia and undergo general anesthesia Lung disease, heart disease, asthma, fever, hypertension, preeclampsia and eclampsia, cardiac arrhythmia Emergency Cesarean Eclampsia and Preeclampsia Multiple pregnancy Spinal anesthesia contraindications (high ICP, hypovolemia, anemia, coagulation disorders, etc.) History of allergy to eggs, soy, midazolam and propofol Use of antiemetic drugs

Design outcomes

Primary

MeasureTime frame
Sedation. Timepoint: We record ramsy sedation score in 24 hours after surgery.?. Method of measurement: Ramsy sedation score.;Nausea & vomiting. Timepoint: After surgery. Method of measurement: Observation.

Secondary

MeasureTime frame
Systolic and Diastolic Blood Pressure. Timepoint: Every 5 minutes (from drug administration until end of surgery). Method of measurement: Non-invasive automatic barometric device.;Heart Rate. Timepoint: Every 5 minutes (from drug administration until end of surgery). Method of measurement: Using a pulse oximeter.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNahid Manouchehrian

Hamedan University of Medical Sciences

manuchehriann@gmail.com+98 81 3827 7012

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026