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The effect of intrauterine human chorionic gonadotropin injection on pregnancy outcomes in infertile patients

The effect of intrauterine human chorionic gonadotropin injection before embryo transfer on the implantation and pregnancy rate in infertile patients: A randomized clinical trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2012091310328N3
Enrollment
159
Registered
2013-01-12
Start date
2012-04-05
Completion date
Unknown
Last updated
2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility. Complications of attempted introduction of embryo in embryo transfe

Interventions

Intervention 1: In control group (n=53) in time of monitoring when at least three follicles 18 mm to be seen on ultrasound, 10,000 units HCG will be injected. 36 hours after puncturing oocytes, IVF

Sponsors

Vise Canceler of Shahid Sadoughi University of Medical Sciences of Yazd, Research and Clinical Cente
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 40 Years

Inclusion criteria

Inclusion criteria: female age in the range of 20-40 years male factor infertility unexplained infertility basal FSH less than 12.

Exclusion criteria

Exclusion criteria: azoospermia, presence of uterine myoma endometriosis hydrosalpinges previous IVF/ICSI trials (successful or unsuccessful) history of endocrine diseases such as diabetes and thyroid dysfunction previous history of hysterocopic operation due to submoucosal myoma, and intrauterine synechia.

Design outcomes

Primary

MeasureTime frame
Implantation rate. Timepoint: Identified through vaginal or abdominal ultrasound 4-5 wks after the embryo transfer. Method of measurement: Observation of number of gestational sacs by transvaginal ultrasonography per 100 embryo transfer.;Chemical pregnancy. Timepoint: 2 weeks after embryo transfer. Method of measurement: BHCG test.;Clinical pregnancy. Timepoint: 4 -5 weeks after embryo transfer. Method of measurement: observation of fetal heart activity by trans vaginal or abdominal ultrasound.

Secondary

MeasureTime frame
Abortion. Timepoint: Before the 20th week of pregnancy. Method of measurement: Abortion product observation (placenta and fetus residual).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr.Sima Janati

Research and Clinical Center for Infertility, Shahid Sadoughi University of Medical Sciences Yazd

janati@dums.ac.ir+98 35 1824 7085

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026