Effect of legume-based DASH diet in patients with polycystic ovary syndrome

The effects of legume-based DASH diet on anthropometric factors, glucose & lipid profiles and testosterone level in women with polycystic ovary syndrome (PCOS): A randomized clinical trial

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20120913010826N33

Enrollment

Registered

2023-06-12

Start date

2023-06-20

Completion date

Unknown

Last updated

2024-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

polycystic ovary syndrome. Polycystic ovarian syndrome

Interventions

Intervention 1: Intervention group: Legume-based DASH diet. DASH diet (Dietary Approaches to Stop High Blood Pressure) that contains 50-55% carbohydrates, 15-20% protein and 25-30% fat. The DASH diet

Eligibility

Sex/Gender

Female

Age

20 Years to 50 Years

Inclusion criteria

Inclusion criteria: Women of reproductive age and before menopause (20-50 years) Women with PCOS according to the Rotterdam criteria Oligomenorrhea or amenorrhea Clinical or laboratory hyperandrogenism

Exclusion criteria

Exclusion criteria: Pregnancy, miscarriage or breastfeeding in the last 6 months Oligomenorrhea caused by secondary causes, including endocrine disorders (congenital adrenal hyperplasia, androgen-secreting tumors, Cushing's syndrome, hyperprolactinemia, adrenal disorders) Previous history or current getting with any cancer History of type 2 diabetes Intrauterine Insemination (IUI) or In Vitro Fertilization) IVF( Special diets or low-calorie diets in the past three months, including vegetarian diets

Design outcomes

Primary

Measure	Time frame
HOMA-IR index. Timepoint: Before intervention and 16 weeks after intervention. Method of measurement: HOMA-IR = (Glu ×Insulin)/405.;Low density lipoprotein cholesterol (LDL). Timepoint: Before intervention and 16 weeks after intervention. Method of measurement: Special kit.;High density lipoprotein cholesterol (HDL). Timepoint: Before intervention and 16 weeks after intervention. Method of measurement: Special kit.;Triglyceride. Timepoint: Before intervention and 16 weeks after intervention. Method of measurement: Special kit.;Total cholesterol. Timepoint: Before intervention and 16 weeks after intervention. Method of measurement: Special kit.;FBS. Timepoint: Before intervention and 16 weeks after intervention. Method of measurement: Special kit.;Serum insulin. Timepoint: Before intervention and 16 weeks after intervention. Method of measurement: Special kit.;Free testosterone. Timepoint: Before intervention and 16 weeks after intervention. Method of measurement: Special kit.	—

Measure

Time frame

HOMA-IR index. Timepoint: Before intervention and 16 weeks after intervention. Method of measurement: HOMA-IR = (Glu ×Insulin)/405.;Low density lipoprotein cholesterol (LDL). Timepoint: Before intervention and 16 weeks after intervention. Method of measurement: Special kit.;High density lipoprotein cholesterol (HDL). Timepoint: Before intervention and 16 weeks after intervention. Method of measurement: Special kit.;Triglyceride. Timepoint: Before intervention and 16 weeks after intervention. Method of measurement: Special kit.;Total cholesterol. Timepoint: Before intervention and 16 weeks after intervention. Method of measurement: Special kit.;FBS. Timepoint: Before intervention and 16 weeks after intervention. Method of measurement: Special kit.;Serum insulin. Timepoint: Before intervention and 16 weeks after intervention. Method of measurement: Special kit.;Free testosterone. Timepoint: Before intervention and 16 weeks after intervention. Method of measurement: Special kit.

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Secondary

Measure	Time frame
Weight, fat mass, fat free mass, RMR, body mass index and visceral fat. Timepoint: Before intervention and 16 weeks after the intervention. Method of measurement: Omron digital Scale.;Waist,Hip circumference. Timepoint: Before intervention and 16 weeks after the intervention. Method of measurement: Meter.;Total energy intake, total nutrients intake. Timepoint: Before intervention and 16 weeks after the intervention. Method of measurement: 24 hour recall.;The length of the menstrual cycle. Timepoint: Before intervention and 16 weeks after the intervention. Method of measurement: questionnaire.	—

Measure

Time frame

Weight, fat mass, fat free mass, RMR, body mass index and visceral fat. Timepoint: Before intervention and 16 weeks after the intervention. Method of measurement: Omron digital Scale.;Waist,Hip circumference. Timepoint: Before intervention and 16 weeks after the intervention. Method of measurement: Meter.;Total energy intake, total nutrients intake. Timepoint: Before intervention and 16 weeks after the intervention. Method of measurement: 24 hour recall.;The length of the menstrual cycle. Timepoint: Before intervention and 16 weeks after the intervention. Method of measurement: questionnaire.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Azadeh Najarzadeh

Yazd University of Medical Sciences

azadehnajarzadeh@gmail.com+98 35 3149 2232

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026