cardiac surgery patients.
Conditions
Interventions
Intervention 1: Intervention group: Intervention group will receive supplement which contains 7 grams of glutamine, 7 grams of arginine and 1.5 grams of hydroxy methylbutyrate. These supplements are g
Sponsors
Yazd University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Willingness to cooperate and complete the informed consent form by the patient Age 18 to 70 years Body mass index (BMI) above 18.5 and below 30 Do not take supplements or formulas to strengthen the immune system before starting the study No infection and sepsis No need for other entral formulas due to special problems (kidney, lung, liver, etc) Candidate patients for heart surgery
Exclusion criteria
Exclusion criteria: Drugs that affect metabolism such as steroids and male and female hormonal drugs or corticosteroids Abnormal liver function Metastatic cancer and autoimmune diseases Patients with thyroid, pituitary and hypothalamus dysfunction
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Biochemical evaluation of interleukin 1 (mean serum interleukin-1 concentration) Biochemical evaluation of interleukin 6 (mean serum interleukin-1 concentration) Biochemical evaluation of TNF-alpha (mean serum TNF-alpha concentration). Timepoint: Before and after of surgery. Method of measurement: Biochemical experiments. | — |
Secondary
| Measure | Time frame |
|---|---|
| Duration of hospitalization in ICU and hospital. Timepoint: After cardiac surgery. Method of measurement: Check the patient file. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Azadeh Nadjarzadeh
Yazd University of Medical Sciences
Outcome results
None listed