"Effect of Supplementation in combination with diet therapy in treatment of polycystic ovary syndrome"

The effect of vitamin D supplementation on anthropometric indices and Leptin serum level in women with polycystic ovary syndrome treated with low calorie diet

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20120913010826N30

Enrollment

Registered

2018-07-31

Start date

2017-08-22

Completion date

Unknown

Last updated

2018-09-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: polycystic ovary syndrome. Condition 2: . Polycystic ovarian syndrome

Interventions

Intervention 1: Intervention group: participants in this group received weight loss diet plus 50000 IU/week vitamin D3 supplementation for 12 weeks. Intervention 2: Control group: participants in thi

Eligibility

Sex/Gender

Female

Age

18 Years to 40 Years

Inclusion criteria

Inclusion criteria: _aged 18-40 years _BMI between 25 to 40 _Serum vitamin D levels less than 20 ng /ml _not using weight loss diet and vitamin D supplement Over the last 3 months _not using hormone therapy _not using certain drugs including Weight loss drugs and multivitamin supplements mineral _not smoking _Patients with PCOS according to Rotterdam criteria _not doing heavy and professional exercise

Exclusion criteria

Exclusion criteria: individuals with diabetes, Cardiovascular disease, Liver, kidney, thyroid and para- thyroid, Cushing's syndrome, osteomalaci _Non-compliance with diet and supplementation _changes in physical activity

Design outcomes

Secondary

Measure	Time frame
Leptin serum level. Timepoint: Befor and after 12 weeks treatment. Method of measurement: Using ELISA.;Weight. Timepoint: Befor and after 12 weeks treatment. Method of measurement: OMRON scale with an accuracy of 0.1kg.;Body mass index. Timepoint: Befor and after 12 weeks treatment. Method of measurement: weight/ height*height.;Weist circumference. Timepoint: Befor and after 12 weeks treatment. Method of measurement: By meter in cm.;Hip circumference. Timepoint: Befor and after 12 weeks treatment. Method of measurement: By meter in cm.;Percent of body fat, percent of free fat mass. Timepoint: Befor and after 12 weeks treatment. Method of measurement: Body composition device.	—

Measure

Time frame

Leptin serum level. Timepoint: Befor and after 12 weeks treatment. Method of measurement: Using ELISA.;Weight. Timepoint: Befor and after 12 weeks treatment. Method of measurement: OMRON scale with an accuracy of 0.1kg.;Body mass index. Timepoint: Befor and after 12 weeks treatment. Method of measurement: weight/ height*height.;Weist circumference. Timepoint: Befor and after 12 weeks treatment. Method of measurement: By meter in cm.;Hip circumference. Timepoint: Befor and after 12 weeks treatment. Method of measurement: By meter in cm.;Percent of body fat, percent of free fat mass. Timepoint: Befor and after 12 weeks treatment. Method of measurement: Body composition device.

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Primary

Measure	Time frame
25OHD (25-hydroxy vitamin D). Timepoint: Befor and after 12 weeks treatment. Method of measurement: Using ELISA.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSamira Jafari-Sfidvajani

Yazd University of Medical Sciences

samira.jafari67@gmail.com+98 25 3294 2208

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026