The effect of vitamin D supplementation in people with sperm motility disorder

The effect of vitamin D supplementation on androgen hormones, sperm motility, and morphology in patients with sperm motility disorder and vitamin D deficiency.

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20120913010826N29

Enrollment

Registered

2018-04-29

Start date

2017-10-16

Completion date

Unknown

Last updated

2018-05-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

asthenozoospermia. Male infertility

Interventions

Intervention 1: In the intervention group, a dose of 50,000 units of vitamin D was administered for 12 weeks (one perl of vitamin D per week for 8 weeks and only one perl of vitamin d administered as

Eligibility

Sex/Gender

Male

Age

20 Years to 45 Years

Inclusion criteria

Inclusion criteria: The desire to participate in the study - men aged 20-45 years old - Passing for at least one year from the time that decide to have a baby and not use contraceptives - sperm motility disorder according to WHO criteria - Not using vitamin D supplements and calcium in the last 3 months- levels of 25 hydroxyvitamin D (25OHD) less than 30 ng / ml

Exclusion criteria

Exclusion criteria: unwillingness to participate - Having varicocele - individuals with azoospermia, cryptorchidism, and microorchidism - History of vasectomy

Design outcomes

Primary

Measure	Time frame
Sperm motility. Timepoint: Before and after intervention. Method of measurement: Semen sample.;Total testosterone. Timepoint: Before and after intervention. Method of measurement: Blood sample.;Sex hormone binding globulin. Timepoint: Before and after intervention. Method of measurement: Blood sample.;Free androgen index. Timepoint: Before and after intervention. Method of measurement: Total testosterone / SHBG.;Sperm morphology. Timepoint: Before and after intervention. Method of measurement: Semen sample.;Sperm concentration. Timepoint: Before and after intervention. Method of measurement: Semen sample.	—

Measure

Time frame

Sperm motility. Timepoint: Before and after intervention. Method of measurement: Semen sample.;Total testosterone. Timepoint: Before and after intervention. Method of measurement: Blood sample.;Sex hormone binding globulin. Timepoint: Before and after intervention. Method of measurement: Blood sample.;Free androgen index. Timepoint: Before and after intervention. Method of measurement: Total testosterone / SHBG.;Sperm morphology. Timepoint: Before and after intervention. Method of measurement: Semen sample.;Sperm concentration. Timepoint: Before and after intervention. Method of measurement: Semen sample.

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Secondary

Measure	Time frame
Body Fat percent. Timepoint: Before and after intervention. Method of measurement: by body composition analyzer.;Weight. Timepoint: Before and after intervention. Method of measurement: by body composition analyzer.;Body mass index. Timepoint: Before and after intervention. Method of measurement: kg/m2.;Muscle mass percent. Timepoint: Before and after intervention. Method of measurement: by body composition analyzer.;Waist circumference. Timepoint: Before and after intervention. Method of measurement: Meter.;Hip circumference. Timepoint: Before and after intervention. Method of measurement: Meter.;Vitamin D. Timepoint: Before and after intervention. Method of measurement: blood sample.	—

Measure

Time frame

Body Fat percent. Timepoint: Before and after intervention. Method of measurement: by body composition analyzer.;Weight. Timepoint: Before and after intervention. Method of measurement: by body composition analyzer.;Body mass index. Timepoint: Before and after intervention. Method of measurement: kg/m2.;Muscle mass percent. Timepoint: Before and after intervention. Method of measurement: by body composition analyzer.;Waist circumference. Timepoint: Before and after intervention. Method of measurement: Meter.;Hip circumference. Timepoint: Before and after intervention. Method of measurement: Meter.;Vitamin D. Timepoint: Before and after intervention. Method of measurement: blood sample.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactAlireza Gheflati

Yazd University of Medical Sciences

alireza.2130@yahoo.com+98 35 3820 9100

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026