Preventing Shivering After Spinal Anesthesia in Cesarean Section Using Intrathecal Ketamine

Evaluation of Intrathecal Ketamine Efficacy in Reducing Post-Spinal Shivering in Cesarean Section: A Double-Blind Randomized Clinical Trial

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20120910010800N14

Enrollment

100

Registered

2025-08-12

Start date

2025-09-23

Completion date

Unknown

Last updated

2025-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Shivering. Chills (without fever)

Interventions

Intervention 1: Intervention group: Receive 12.5 mg of hyperbaric bupivacaine with 0.1 mg/kg of ketamine intrathecally by an anesthesiologist to provide anesthesia for cesarean section surgery. Interv

Eligibility

Sex/Gender

Female

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Pregnant women over 18 years Scheduled for elective cesarean section under spinal anesthesia ASA physical status I or II Weight = 50 kg Signed informed consent

Exclusion criteria

Exclusion criteria: Known neurological or psychiatric disorders Renal, hepatic, or cardiac insufficiency; diabetes mellitus Allergy to ketamine or bupivacaine Long-term use of antiepileptic drugs Conversion to general anesthesia or surgery lasting over 2 hours

Design outcomes

Primary

Measure	Time frame
Shivering. Timepoint: Continuous observation of the patient at any time during the observation. Method of measurement: Bedside Shivering Assessment Scale (BSAS).	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDariush Abtahi

Shahid Beheshti University of Medical Sciences

d.abtahi@sbmu.ac.ir+98 21 2263 2611

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026