Comparison of pentoxifylline and tacrolimus in the treatment of vitiligo patients

comparing the additive effect of topical pentoxifylline and phototherapy versus topical tacrolimus and phototherapy inpateints with vitiligo

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20120909010795N3

Enrollment

Registered

2019-05-09

Start date

2017-08-23

Completion date

Unknown

Last updated

2019-05-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

vitiligo. Vitiligo

Interventions

Intervention 1: Intervention group: 35 vitiligo lesions have been treated locally with pentoxifylline in patients with NBUVB treated light therapy. Pentoxifylline was 10% in the form of a topical crea

Eligibility

Sex/Gender

All

Age

14 Years to 70 Years

Inclusion criteria

Inclusion criteria: Patients with vitiligo (with clinical diagnosis and Wood's Lamp) Patients with at least two relatively and bilateral lesion. Patients undergoing treatment with NBUVB Residence in Shiraz, in case of non-residence in Shiraz, may attend meetings required for a visit. Having the ability to understand Persian language written consent to participate in the study.

Exclusion criteria

Exclusion criteria: Over the last three months, they have received topical vitiligo medication Unwillingness to receive local interventions

Design outcomes

Primary

Measure	Time frame
Pigmentation. Timepoint: At the beginning of the study, one month and three months after starting treatment. Method of measurement: Qualitative measure with VASI score and quantitative measurement with dermocatch tool.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNasrin Saki

Shiraz University of Medical Sciences

sakina@sums.ac.ir+98 71 3231 9049

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026