lower limb bone fracture. Disorders of continuity of bone
Conditions
Interventions
Intervention 1: sufentanil Group: we will administrate intrathecally 15mg Bupivacaine 0.5% (Bupivacaine®? Milan Co? Italy) with 5 microgram Sufetanil (Sufenta? Janssen-Cilag, India). Intervention 2:
Treatment - Drugs
sufentanil Group: we will administrate intrathecally 15mg Bupivacaine 0.5% (Bupivacaine®? Milan Co? Italy) with 5 microgram Sufetanil (Sufenta? Janssen-Cilag, India)
Fentnyll group: we will administrate intrathecally 15mg Bupivacaine 0.5% (Bupivacaine®? Milan Co? Italy) with 25 microgram fetanyl (Fentanyl, Abureyhan, Iran)
Control group: we will administrate intrathecally 15mg Bupivacaine 0.5% (Bupivacaine®? Milan Co? Italy) with 0.5 ml Distilled water
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: adults aged 18-65 years; American Society of Anesthesiology classification of 1-2; No contraindication for spinal anesthesia; No history of opium abuse; No history of neurologic, neuromuscular or psychological disorders; no history of allergic reaction to local anesthetic Exclusion criteria: request for analgesic drugs or opioids during spinal anesthesia; need for general anesthesia during operation; pregnancy
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mean Arterial Pressure. Timepoint: every 2 min til 20 min, then every 5 min until transfering the patient to the recovery then every 15 min until transfering to the ward. Method of measurement: Electronic sphygmometer. | — |
Secondary
| Measure | Time frame |
|---|---|
| O2 Saturation. Timepoint: every 2 min til 20 min, then every 5 min until transfering the patient to the recovery then every 15 min until transfering to the ward. Method of measurement: pulse oximetry.;Heart rate. Timepoint: every 2 min til 20 min, then every 5 min until transfering the patient to the recovery then every 15 min until transfering to the ward. Method of measurement: pulse oximetry.;Maximum height of sencory block. Timepoint: 10 min after intervention. Method of measurement: physcial examination.;Ephedrin administration. Timepoint: when blood pressure decrease to20% of base or below 100mmhg. Method of measurement: yes/ no.;Bradicardia. Timepoint: when Heart rate decreases below 60 per min. Method of measurement: pulse oximetry. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactValiollah Hassani
Tehran University of Medical Sciences
Outcome results
None listed