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Comparing effects of Isoflurane and propofol on body temperature changes during knee arthroscopy surgery

Comparing effects of Isoflurane and Propofol on body temperature changes during knee arthroscopy surgery

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT2012090410741N1
Enrollment
40
Registered
2012-12-23
Start date
2012-08-22
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee Arthroscopy for treatment and diagnosis of knee ligaments tearing. Disorders of synovium and tendon

Interventions

Intervention 1: In group 1 Isoflurane (MAC
0.8-1.2)
Premedication and induction medicines in both groups are similar, including Midazolam (2mg), Fentanyl ( 2µgr/kg ) for premedication and STP 5mg/kg - 0/5mg/kg/ Atracurium for induction. N2O%50 is admin
Treatment - Drugs
In group 1 Isoflurane (MAC
In group 2 Propofol (200mg/kg/min)

Sponsors

Kerman Univesity of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: All patients (18 to 50 years) candidate for knee arthroscopy under general anesthesia. Exclusion criteria: Coagulation and bleeding disorders; history of nasal bleeding, drug abusers; blood transfusion during surgery; endocrine disorders for example thyroid disease, kidney disease, hepatitis, high blood pressure, psychiateric disorders and history of allergy to propofol or narcotics; operation time more than 1.5 hour; hemodynamic instability during anesthesia.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Core body temprature. Timepoint: every 10 minuts during anesthesia and after extubation. Method of measurement: Degree celsius by tympanic thermometer.

Secondary

MeasureTime frame
Post operative shivering. Timepoint: from extubation till departuring of recovery room every 10 minuts. Method of measurement: classification of shivering.;Blood pressure. Timepoint: every 10 minuts at the time of taking core body temprature. Method of measurement: electronic blood pressure monitoring.;Peripheral body temperature. Timepoint: every 10 minuts at the time of taking core body temprature. Method of measurement: oral thermometer.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohamadhassan Asskari

Kerman Univesity of Medical Sciences

askarimohamadhasan@yahoo.com+98 34 1211 5806

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026