hypertension. Essential (primary) hypertension
Conditions
Interventions
Intervention 1: 50000IU vitamin D3 pearl(oral supplements),for 8 weeks, one pearl per week. Intervention 2: placebo pearl, for 8 weeks, one pearl per week.
Treatment - Drugs
Placebo
50000IU vitamin D3 pearl(oral supplements),for 8 weeks, one pearl per week
placebo pearl, for 8 weeks, one pearl per week
Sponsors
Vice chancellor for research, Shahid Sadoogi University of Medical Sciences
Eligibility
Sex/Gender
All
Age
25 Years to 50 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: patients with Systolic Blood Pressure equal or more than 140 mmHg ; and Diastolic Blood Pressure equal or more than 90 mmHg. ; and serum 25-hydroxy vitamin D3 lower than 30 ng/ml ; living in Yazd province; aged 25-50 years; not to be alcohol user or smoker or addicted ; without any liver or Coronary-artery or renal or Gastro Intestinal disorders; not using oral or injection of corticosteroids; not using cardiac glycosides or antiepileptic drugs; not using multi vitamins or supplements containing vitamin D, Calcium, Magnesium, Phosphorus or their analogs in past 3 mounts; not using injection of vitamin D in past 6 mounts; Exclusion criteria: any change in dosage or type of anti hypertension drugs; not following the study protocol. Exclusion criteria: any change in dosage or type of anti hypertension drugs; not following the study protocol.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hypertension. Timepoint: before and 8 week after intervention. Method of measurement: mercurial sphygmomanometer. | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum Calcium. Timepoint: before and 8 weeks after intervention. Method of measurement: laboratory biochemical measurements.;Serum 25- Hydroxy vitamin D. Timepoint: before and 8 weeks after intervention. Method of measurement: laboratory biochemical measurements _nmol/lit.;Serum PTH. Timepoint: before and 8 weeks after intervention. Method of measurement: laboratory biochemical measurements.;Serum phosphorus. Timepoint: before and 8 weeks after intervention. Method of measurement: laboratory biochemical measurements. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Mohammadreza Mirjalili
Shahid sadoogi University Of Medical Sciences and Health Services
Outcome results
None listed