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The effect of antibiotic prophylaxis in the prevention of surgical site infection after hernia surgery

Evaluation of prophylactic antibiotic in prevention of surgical site infection in inguinal hernioplasty with mesh in patients referring Isfahan's Dr. Shariati Hospital

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2012090210719N1
Enrollment
100
Registered
2012-11-28
Start date
2012-09-22
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

inguinal hernia. Unilateral or unspecified inguinal hernia, without obstruction or gangrene

Interventions

Intervention 1: 10 cc intravenous sterile saline 30-45 min before surgery in control group. Intervention 2: 1 gr intravenous cefazolin 30-45 minutes before surgery in case groupe.
Placebo
Prevention
10 cc intravenous sterile saline 30-45 min before surgery in control group
1 gr intravenous cefazolin 30-45 minutes before surgery in case groupe

Sponsors

Islamic Azad University, Najafabad Branch
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to 149 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: all male patients with Primary Inguinal Hernia who are candidates for elective hernioplasty with mesh. Exclusion criteria: patients younger than 18 years old; patients with a recurrent, strangulated, giant scrotal or femoral hernia; patients who are indicated for emergency hernia surgery; patients with a history of diabetes mellitus; patients with underlying heart, liver, renal disease, AIDS or malignancy; patients with American Society of Anesthesiologists (ASA) scores more than II; patients treated with glucocorticoid; patients with allergy to the given antibiotic; patients taking some antibiotic 3 days prior to surgery; Use of drain; refusing to participate in the study.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Surgical site infection. Timepoint: 1, 6-8 and 12 weeks after operation. Method of measurement: Clinical exam, culture and questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactShahriar Barkhordary

Islamic Azad University, Najafabad Branch

shbarkhordary@gmail.com+98 31 1626 5032

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026