cognition. Other symptoms and signs involving cognitive functions and awareness
Conditions
Interventions
Intervention 1: Intervention: Dexemedetomidine (0.5µg/kg) as an IV, bolus dose in 10 minutes slowly and 5 minutes before starting the topical anesthesia. The infusion dose will administer by 0.2 µg/kg
Diagnosis
Intervention: Dexemedetomidine (0.5µg/kg) as an IV, bolus dose in 10 minutes slowly and 5 minutes before starting the topical anesthesia. The infusion dose will administer by 0.2 µg/kg/hr for maintena
Control: Remifentanil (0.1µg/kg) as a bolus dose in 10 minutes slowly and 5 minutes before topical anesthesia. The infusion dose will administer 0.05 µg/kg/min for maintenance during the surgery.
Sponsors
Vice- Chancellor in Research Affairs, Shahid Beheshti University of Medical Sciences
Eligibility
Sex/Gender
All
Age
40 Years to 70 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Age between 40 to 70 years old; ASA Class Iⅈ Mustard gas veterans under topical cataract surgery Exclusion criteria: Nausea and Vomiting more than 3times; Surgery time more than 120min; Any problem with the medicine protocol; initial MMSE score less than 23; Heart rate less than 45
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Heart rate. Timepoint: Just befor injection the anesthetic agents then every 5 minutes during the surgery. Method of measurement: ECG Monitoring.;Blood pressure. Timepoint: Just befor injection the anesthetic agents then every 5 minutes during the surgery. Method of measurement: non invasive blood pressure monitoring.;SPO2. Timepoint: Just befor injection the anesthetic agents then every 5 minutes during the surgery. Method of measurement: Pulse oximetry. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMahtab Poor Zamany Nejat Kermany
Faculty Member of Shaheed Beheshti University of Medical science
Outcome results
None listed