The effect of myoinositol supplementation on the prevention of gestational diabetes mellitus

The effect of myoinositol supplementation on the prevention of gestational diabetes mellitus in high-risk women

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20120826010664N4

Enrollment

276

Registered

2019-05-08

Start date

2019-02-20

Completion date

Unknown

Last updated

2024-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gestational diabetes mellitus (GDM). Gestational diabetes mellitus

Interventions

Intervention 1: Intervention group: 2 gr of myoinositol plus 200 micro gr folic acid twice a day orally, from 14th week of gestation until 28th week. Intervention 2: Control group: 200 micro gr folic

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: BMI>30 Family history of type 2 diabetes Previous history of GDM Glucosoria Glucose metabolism disorder history of infant macrosomia

Exclusion criteria

Exclusion criteria: History of diabetes mellitus Multiple pregnancy Acute infection during pregnancy Impaired GTT in first-trimester routine tests

Design outcomes

Primary

Measure	Time frame
Gestational diabetes mellitus. Timepoint: 24- 28 weeks of pregnancy. Method of measurement: glucose tolerance test.	—

Secondary

Measure	Time frame
Type of delivery. Timepoint: end of pregnancy. Method of measurement: observational.;Macrosomia. Timepoint: After child birth. Method of measurement: observational.;Preterm labor. Timepoint: end of pregnancy. Method of measurement: observational.;Preeclampsia. Timepoint: end of pregnancy. Method of measurement: observational.;Premature rupture of membranes (PROM). Timepoint: end of pregnancy. Method of measurement: observational.;Intrauterine growth restriction (IUGR). Timepoint: end of pregnancy. Method of measurement: observational.	—

Measure

Time frame

Type of delivery. Timepoint: end of pregnancy. Method of measurement: observational.;Macrosomia. Timepoint: After child birth. Method of measurement: observational.;Preterm labor. Timepoint: end of pregnancy. Method of measurement: observational.;Preeclampsia. Timepoint: end of pregnancy. Method of measurement: observational.;Premature rupture of membranes (PROM). Timepoint: end of pregnancy. Method of measurement: observational.;Intrauterine growth restriction (IUGR). Timepoint: end of pregnancy. Method of measurement: observational.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Reihaneh Pirjani

Tehran University of Medical Sciences

pirjani@razi.tums.ac.ir+98 21 7788 3288

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026